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Valproic acid causes brain stem cell senescence in embryo

Valproic acid causes brain stem cell senescence in embryo

How Valproic Acid Causes Neurodevelopmental Abnormalities in Exposed Children in utero ? While other antiepileptics such as topiramate also appear to be involved, the underlying mechanisms remain poorly understood. French researchers show in a study on human brain organoids and in animal models that the antiepileptic induces excessive senescence of embryonic brain stem cells. This …

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